BioPOLIM - Polarised Fluorescence

BioPOLIM - Polarization resolved fluorescence microscopy

methods

2D polarization resolved fluorescence microscopy
polarization resolved scanning confocal microscopy
polarization resolved wide field microscopy

areas of research

Protein Aggregation visualized using 2D polarization imaging

Aggregation of F-Actin in cells and tissue

S. Cheng, S. Gjeci, A. Rusevski, P. Then, E. Sunil, S. Adak, H.-D. Arndt, R. Heintzmann, A.T. Press, D. Täuber 57th Winter Seminar - Biophysical Chemistry, Molecular Biology and Cybernetics of Cell Functions, Klosters, Switzerland, January 2024. doi:10.13140/RG.2.2.14239.33443
D. Täuber, J. Shi, P. Babic, K.-J. Benecke, M. Bauer, R. Heintzmann, I.G. Scheblykin, and A.T. Press, European Light Microscopy Initiative 2021, June 2021. doi: 10.22443/rms.elmi2021.6
P. Martinac, A.T. Press, A. Medyukhina, K.-J. Benecke, J. Shi, D. Täuber, S. Hoeppener, Z. Cseresnyes, I.G. Scheblykin, M.H. Gräler, I. Rubio, M.-T. Figge, U.S. Schubert. M. Bauer, 9th International Congress "Sepsis and Multiorgan Dysfunction", Infection, 47, S6-S7, 2019. doi: 10.1007/s15010-019-01341-2
D. Täuber, A.T. Press, P. Martinac, K.-J. Benecke, M. Bauer, J. Shi, R. Camacho, I.G. Scheblykin, Laserlab Europe User Meeting, Paris, France, November 2018. book of abstracts

Aggregation of human alpha-synuclein in a mouse model ex vivo

R. Camacho, D. Täuber, C. Hansen, J. Shi, L. Bousset, R. Melki, J.-Y. Li, I.G. Scheblykin, Communications Biology, 1, 157, 2018. doi: 10.1038/s42003-018-0156-x

Organic photo electronics (OPE)

2D polarization imaging of conjugated polymer films for OPE

X. Luo, Y. Xue, W. Cai, D. Täuber, I. Malovicho, B. Sava, L. Ma, G. Cen, X. Lu, C. Zhao, I.G. Scheblykin, J. Yu, W. Mai, F. Liu, E. Wang, L. Hou: Intrinsic Polarization-Sensitive Organic Photodetector with Self-Assembled All-Polymer Heterojunction, Applied Physics Letters, 121, 233301, 2022. doi: 10.1063/5.0128850.
R. Camacho, D. Täuber, I.G. Scheblykin, REVIEW: Fluorescence anisotropy reloaded – emerging polarization microscopy methods for assessing chromophores’ organization and excitation energy transfer in single molecules, particles, thin films and beyond. Advanced Materials, 31, 1805671, 2019. doi: 10.1002/adma.201805671
D. Täuber, W. Cai, O. Inganäs, I.G. Scheblykin, ACS Omega, 2(1), 32-40, 2017. ACS Live Slide Presentation, doi: 10.1021/acsomega.6b00264
D. Täuber, Y. Tian, Y. Xia, O. Inganäs, I.G. Scheblykin, J. Phys. Chem. C, 121(40), 21848-21856, 2017. doi: 10.1021/acs.jpcc.7b05244
D. Täuber, W. Cai, Y. Xia, O Inganäs, I.G. Scheblykin, in: „Self-Assembly in the world of polymers, 80th Prague Meeting on Macromolecules,“ eds: P. Stepanek, J. Kotek, Institute of Macromolecular Chemistry of the Academy of Sciences of the Czech Republic, ISBN 978-80-85009-85-9, p. 85, 2016.

Photoluminescence polarization properties of (organo-)metal halide perovskite

M. Goldmann, J. Shi, J. Chen , M.E. Messing, K. Zheng, T. Pullerits, I.G. Scheblykin, D. Täuber, in preparation.
D. Täuber, A. Dobrovolsky, R. Camacho, I.G. Scheblykin, Nano Letters, 16(8), 5087–5094, 2016. doi: 10.1021/acs.nanolett.6b02012

Thin liquid crystal films

D. Täuber, K. Radscheit, C. von Borczyskowski, M. Schulz, and V. Al. Osipov, Phys. Rev. E, 94(1), 012804, 2016. doi: 10.1103/PhysRevE.94.012804 arXiv
D. Täuber, and C. von Borczyskowski, REVIEW: Single Molecule Studies on Dynamics in Liquid Crystals. Int. J. Mol. Sci., 14, 19506-19525, 2013. doi: 10.3390/ijms141019506
B. Schulz, D. Täuber, J. Schuster, T. Baumgärtel, and C. von Borczyskowski, Soft Matter, 7(16), 7431 - 7440, 2011. doi: 10.1039/C1SM05434A open access by TU Chemnitz/DFG
B. Schulz, D. Täuber, F. Friedriszik, H. Graaf, J. Schuster and C. von Borczyskowski Phys. Chem. Chem. Phys., 12(37), 11555-11564, 2010. doi: 10.1039/C004042H

projects & grants

DAAD-GSSP Scholarship project Evaluation of pathogenic structures in cells and tissue using polarization-resolved fluorescence microscopy & machine learning (October 2021 - September 2024) for Mohammad Soltaninezhad in the Microscopy Department of Rainer Heintzmann at the Leibniz Institute of Photonic Technology, Jena & Nanoimaging (Nanobiophotonics) Group at Friedrich-Schiller University, Jena.

DFG project funding Ta 1049/2 Live Cell 2D polarization imaging (Live2DPOLIM) – an imaging technique for observation of nanoscale protein aggregation and molecular (re-)arrangements in live cells (June 2020 - Dec 2023) for Daniela Täuber in the Microscopy Department of Rainer Heintzmann at the Leibniz Institute of Photonic Technology, Jena & Nanoimaging (Nanobiophotonics) Group at Friedrich-Schiller University, Jena.

Laserlab-Europe access grant LLC002451 in 2018 Investigation of apical f-actin aggregation in healthy and cholestatic liver tissue using 2D polarisation imaging to Lund Laser Center SMS group of Ivan Scheblykin for Daniela Täuber together with Adrian Press, head of the Nanophysiology Group, Friedrich-Schiller-University Hospital Jena. Receiving funding from the European Union's Horizon 2020 research and innovation programme under grant agreement no 654148 Laserlab-Europe.

DFG personal research grant Ta 1049/1 2D polarisation resolved optical spectroscopy on macromolecules (conjugated polymers and proteins) in different environments for investigation of conformation, aggregation and energy transfer with the intention to improve organic solar cells (October 2014 - March 2016) for Daniela Täuber in the Single molecule spectroscopy group of Ivan Scheblykin at Lunds Universitet, Sweden.

collaboration

	Nanophysiology, Jena University Hospital, Germany
	Center for Sepsis Control & Care, Jena University Hospital, Germany
	Single Molecule Spectroscopy, Lund University, Sweden
	Biomolecular and Organic Electronics, Linköping University, Sweden
	Neural Plasticity and Repair, BMC, Lund University, Sweden
	e-COST Action MP1302 Nanospectroscopy

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